Clinical Science You and Your Patients Trust

At Lifespan Health Science™, our mission is to improve health through science. With multiple high-quality clinical studies, Adipromin™  Weight Management Complex is a product that you can confidently recommend to your patients.

Prescribe Adipromin
  • ^‡* COMPARED TO DIET AND EXERCISE ALONE

Composition

Modern Science Improves on Traditional Remedies

Adipromin is a patented formulation of three standardized herbal extracts: turmeric (Curcuma longa), moringa (Moringa oleifera) and curry leaf (Murraya koenigii). Building on their traditional use in Ayurvedic and other medical traditions, these botanical extracts were screened for activity in a sophisticated assay for inhibition of lipogenesis and differentiation of 3T3-L1 adipocytes. Different combinations and ratios were tested experimentally until one was discovered that outperformed the others, and ultimately went on to become Adipromin. The botanical extracts in Adipromin are responsibly harvested, non-GMO, and traceable from the finished product directly back to the fields where they were grown.

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Support For A Holistic Weight Management

Healthy weight management is about more than shedding pounds. Healthy and sustainable changes to body weight must involve supporting other related systems, like cardiovascular and metabolic health. The clinical trials of Adipromin Weight Management Complex validate its role as part of an integrated holistic health management program. Adipromin has been shown to affect not only body weight and BMI, but also lean body mass, blood lipids, and underlying biochemical mediators—such as adiponectin—that control visceral adiposity, glucose regulation, insulin sensitivity, inflammation metabolism, lipid metabolism, and more.*

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  • Supporting Weight Management by Enhancing Lipolysis 

    Adipromin is not a stimulant or appetite suppressant. It does not interfere with absorption of fat or sugar, nor does it create a sense of fullness. Preclinical research shows that Adipromin modulates lipolysis and lipogenesis: inhibiting lipid accumulation in adipocytes, slowing differentiation and maturation of adipocytes, and reducing intracellular triglyceride content.†1 These actions are thought to be due to the down-regulation of transcription factors PPAR‐gamma and C/EBP. Adipromin has also been shown in animal research to reduce adiposity associated with increased energy intake, while significantly increasing resting energy expenditure (REE).2 Preclinical toxicological research has demonstrated the safety of the formulation.3

Fig. 1 Reductions in body weight and in waist circumference of Adipromin vs placebo. Dixit K et al. Diabetes Obes Metab. 2018 Nov;20(11):2633‐2641.

Consistent, Steady Results Shown in Both Women and Men

Study Results

The clinical efficacy of Adipromin has been demonstrated in three randomized, double-blind, placebo-controlled clinical trials, published in well-respected medical journals.4, 5, 6 To
validate weight management claims, health professionals and regulatory
agencies alike prefer to see at least two clinical trials published in
the peer-reviewed medical literature.

The second, larger study was a randomized controlled
clinical trial of Adipromin in healthy overweight subjects (n = 140).
The 16-week study compared the use of Adipromin in conjunction with an
1800 calorie/day diet and walking plan to a placebo with the same diet
and walking plan.5

At the end of the study, subjects taking Adipromin showed
significant reductions in body weight (-11.82 pounds vs. -1.92 pounds; p
< 0.0001) and BMI (2.05 kg vs. 0.34 kg/m2; p < 0.0001), compared
with placebo.*

Subjects taking Adipromin had significant reductions in waist
circumference (-2.12 inches vs. -0.67 inches; p < 0.0001) and hip
circumference (-1.77 inches vs. -0.47 inches p < 0.0001) compared
with placebo.*

Subjects taking Adipromin had statistically significant improvement
compared to placebo in their blood lipid profiles (p < 0.0001). *

Subjects taking Adipromin had improved serum adiponectin (p =
0.0071) and serum ghrelin (p = 0.0568) compared to those taking
placebo.*

The third clinical trial was a randomized,
double-blind, placebo-controlled clinical trial that assessed the
effects of 7 days of Adipromin supplementation on resting metabolic rate (RMR), heart rate, blood pressure, and indices of mood in healthy overweight men and women.6 Adipromin
produced significant increases in RMR in healthy overweight men and
women relative to those RMR changes measured in a matched placebo group.* The increase in RMR (up to 15.2% after one week) occurred without concomitant alterations in heart rate or blood pressure and was accompanied by an improved measure of mood.*

Holistic Weight Management - Natural Interventions for Weight Loss

Partnering With You To Improve Health

Lifespan Health Science is a purpose-driven company, passionate about helping people live their best lives. We are health professionals, scientists, researchers, innovators of ingredients and products. We work with the best of nature to create life-enhancing supplements and functional foods.

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